322 Charlton Avenue is a 2 1/2 story, 5 bay, irregular plan, stucco-clad, Tudor Revival-influenced, residential building. Built c. 1920, the house is composed of two sections set at an approximate ninety degree angle to each other to accommodate the corner lot. The house is dominated by a green clay tile side gable roof with massive brick chimneys ending in clay pots. The house features ogee-arched window groupings with leaded glass and shed dormers.