366 Montrose Avenue is a 2 1/2 story, 3 bay, rectangular plan, Colonial Revival, wood frame, residential building. Built c. 1900, the clapboard-clad house has a hipped roof with cross gables and a front-facing Palladian dormer. Additional features include semi-hexagonal bays, and a Doric column-supported full front porch. The house was constructed for Isabella Whyte. Although there are inappropriate replacement windows on the second floor, the house is still contributing to the historic district.