377 Charlton Avenue is a 2 1/2 story, 3 bay, rectangular plan, eclectic, wood frame, residential building. The c. 1920 wood shingle-clad house has a gambrel roof, second story shed dormer surmounted by a third story shed dormer, a full wooden entablature with cornice-line dentils, and a full, paired Ionic column-supported porch. Additional architectural ornamentation includes: rubblestone and brick basement and column piers, leaded sidelights, leaded second floor transoms, and a classicizing window surround on the second story windows.