377 Vose Avenue is a 2 1/2 story, 3 bay, rectangular plan, wood frame, eclectic, residential building. Constructed c. 1885, the patterned slate-clad, side gable-roofed house features gabled dormers with knee bracket-supported rafters, and a stickwork portico. Although the house has been somewhat altered over time, it retains enough integrity to be considered contributing to the historic district. Previous owners of the house have attributed it to the work of Richard M. Upjohn, architect, son of Richard Upjohn who designed Trinity Church in New York. The house is said to have been designed for a prominent New York Family: The Tyng Family. Photographic records indicate that the house originally had stick style details and a wrap-around porch. The original carriage house (no longer standing) had three horse stalls, a boxstall for a pony, a harness room, room for several carriages and a big hay loft.